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Pak. J. Bot., 42(1): 523-526, 2010.

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ANTIMICROBIAL SCREENING OF IMPATIENS BICOLOR ROYLE

Muhammad nisar^1*, MUGHAL qayum^2*, MUHAMMAD RAZA shah³, Waqar Ahmad KALEEM², IHSAN ALI¹ AND M. ZIA-Ul-Haq⁴

Abstract: Extracts of Impatiens bicolor Royle obtained from n-hexane (A); dichloromethane (B), ethyl acetate (C), n-butanol (D), aqueous (E) as well as crude (F) were tested In vitro for their antibacterial and antifungal activities. Antibacterial study performed against 6 bacteria viz., Escherichia coli, Bacillus subtilis, Shigella flexenari, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella typhi indicated that crude and its fractions had no activity at all against any microorganism. The antifungal activity of these extracts was performed against 6 fungi viz., Trichophyton longifusus, Candida albicans, Aspergilus flavus, Microsporum canis, Fusarium solani and Candida glaberata. The extracts showed moderate activity against different fungal strains.

¹Institute of Chemical Sciences, University of Peshawar, Peshawar-25120, NWFP, Pakistan

²Department of Pharmacy, University of Peshawar, Peshawar, 25120, Pakistan

³H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan

⁴Department of Pharmacognosy, University of Karachi, Karachi-75270, Pakistan