Pak. J. Bot., 42(5): 3229-3237, 2010.

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			Updated: 06-12-10
	IN VITRO CYTOTOXIC EFFECTS OF METHANOL EXTRACTS OF SIX HELICHRYSUM TAXA USED IN TRADITIONAL MEDICINE HALIL ERHAN EROĞLU^1, ÜMIT BUDAK¹, ERGIN HAMZAOĞLU¹, AHMET AKSOY²AND SEVIL ALBAYRAK² Abstract:* Helichrysum Mill., (Asteraceae) species have been used in folk medicine for thousands of years in the world. The In vitro cytotoxic effects in human lymphocytes of 6 Helichrysum taxa used in Turkey folk medicine were investigated. Blood samples were obtained from healthy donors, non-smoking volunteers, which were incubated and exposed to increasing concentrations of methanol extracts of Helichrysum taxa (0.01, 0.05, 0.1, 0.5 and 1 mg/mL). According to results, other taxa outside H. peshmenianum and H. goulandriorum affected MN rates at high concentrations (0.5 and 1 mg/mL). However mitotic and replication indexes rates of H. pallasii and H. chionophilum did not show a cytotoxic effect. ¹Department of Biology, Faculty of Science and Arts, Bozok University, 66200, Yozgat, Turkey. ²Department of Biology, Faculty of Science, Erciyes University, 38039, Kayseri, Turkey.

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