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CHEMISTRY OF SOME SPECIES GENUS LANTANA

HIDAYAT HUSSAIN¹*, JAVID HUSSAIN^1,2*, AHMED AL-HARRASI¹ AND ZABTA KHAN SHINWARI³

Abstract: This review presents the currently known phytochemical constituents of the genus Lantana; a total of 160 natural compounds have been included. Lantana is free from diterpenoids and rich in essential oils. Monoterpenes, triterpenes, flavones coumarin, steroids, iridoid glycosides, and caffeic acid derivatives are reported from Lantana. Triterpenes and flavones are the more common secondary metabolites in Lantana. Lantana plants are used in folk medicine in many parts of the world. The genus Lantana also produces a number of metabolites in high quantities and some have been shown to possess useful biological activities. The ethnopharmacology, phytochemistry and toxicity of Lantana are considered. The biological activities exhibited by some of the metabolites are discussed and the results of recent studies on the triterpene inhibitors of human a-thrombin discovered in this plant are presented.

¹Department of Biological Sciences and Chemistry, College of Arts and Sciences, University of Nizwa, Birkat Al-Mouz, Nizwa 616, Sultanate of Oman

²Department of Chemistry, Kohat University of Science and Technology, Kohat, Pakistan

³Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan

^*Corresponding author e-mail: Hidayat110@gmail.com (H. Hussain) javidhej@yahoo.com (J. Hussain)