12199 10.30848/PJB2024-6(30) <p> Unveiling the therapeutic prospective of active phytochemicals from <em>Fagonia</em> species and potential role of its green synthesized nanoparticles</p> Iffat Nayila, Sumaira Sharif, Madeeha Shahzad Lodhi, Farhana Aman, Saima Zaheer and Anum Sajid <p> The genus<em> Fagonia</em> of the family Zygophyllaceae consists of species, mostly distributed in tropical-subtropical or warm-temperate regions of the world in different environmental conditions<em>. Fagonia</em> is a convenient herbal medicinal plant with a wide range of therapeutic potentials against different diseases. Numerous studies conducted to explore herbal chemistry and biological functions of <em>Fagonia </em>species. <em>In vivo</em> pharmacological examination of <em>Fagonia </em>species revealed noteworthy characteristics like cytotoxic and anti-cancer potential. Novel chemical ingredients found in the species included flavonoids, alkaloids, terpenoids, vitamins, and nutritional components. Numerous researches conducted on <em>Fagonia</em> species has been compiled in this review study. Using references from significant databases, it comprises a thorough review of the literature about the therapeutic usefulness and bioactivities of several extracts identified from <em>Fagonia </em>species. The areas covered in current review reveal details about the immense medicinal value of the different components of <em>Fagonia</em> species, presence of bioactive constituents as well as therapeutic efficacy of nanoparticles synthesized by using <em>Fagonia </em>plant extract, illustrating the advantages of using nanotechnology and green synthesis nanoformulation of herbal plants</p> Published 2024 56 6 2295 2303