PJB-2010-335
IN VITRO CYTOTOXIC EFFECTS OF METHANOL EXTRACTS OF SIX HELICHRYSUM TAXA USED IN TRADITIONAL MEDICINE
HALIL ERHAN EROĞLU1*, ÜMIT BUDAK1, ERGIN HAMZAOĞLU1, AHMET AKSOY2 AND SEVIL ALBAYRAK2
DOI:
Abstract
Helichrysum Mill., (Asteraceae) species have been used in folk medicine for thousands of years in the world. The In vitro cytotoxic effects in human lymphocytes of 6 Helichrysum taxa used in Turkey folk medicine were investigated. Blood samples were obtained from healthy donors, non-smoking volunteers, which were incubated and exposed to increasing concentrations of methanol extracts of Helichrysum taxa (0.01, 0.05, 0.1, 0.5 and 1 mg/mL). According to results, other taxa outside H. peshmenianum and H. goulandriorum affected MN rates at high concentrations (0.5 and 1 mg/mL). However mitotic and replication indexes rates of H. pallasii and H. chionophilum did not show a cytotoxic effect.
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