Paper Details

PJB-1969-2

CAUSES OF THE FORMATION OF AN ABNORMALLY HIGH PROPORTION OF PROTOTROPHS IN SOME INTERALLELIC CROSSES OF NEUROSPORA CRASS

MAJEED AIIMAD, M. ISLAM AND R. KIIANAM
DOI:


Abstract

Causes of the formation of a high frequency of prototrophs in inter allelic crosses of three tryptophan-1 mutants and one tryptophan-3 mutant have been investigated. The high frequency of prototrophs in the inter allelic crosses of the three tryptophan-l mutants follows from the formation of a large number of pseudo-wild spores. But the formation of an abnormally high proportion of prototrophs in the interallelic crosses of the single tryptophan-3 mutant, A30S, cannot be explained on the basis of pseudo-wild formation, action of recombination, accelerating genes, unequal crossing over, reversion of suppressors. It seems that the. tryptophan synthetase formed by the damaged tryptophan-3 locus in this mutant can acquire a functioned configuration as a result of the action of some other genes which act as modifiers.

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