Paper Details

PJB-1988-32

Assessment of possible mutagenicity of betel leaf in saccharomyces cerevisiae

S.R. chughtai , akbar S. mohmand and B.A. siddiqi
DOI:

Abstract

---

Aqueous extract of betel leaf was tested for the induction of mitotic gene conversion, mitotic crossing over and reverse mutation in diploid strains of saccharomyces cerevisiae . tests performed with stationary and log phase cells showed that betel leaf extract was non-mutagenic in yeasts without metabolic activation . it failed to increase the frequency of convertants , recombinants and revertants. Betel leaf extract neither caused cell killing nor inhibition of cell divisions . EMS, used as control , exhibited mutagenic and recombinogenic activity.

To Cite this article:
Download