PJB-2023-67
PSYLLIUM SEED MUCILAGE HAS BEEN ISOLATED AND CHARACTERISED PHYSICOCHEMICALLY FOR USE AS A TRUSTWORTHY PHARMACEUTICAL EXCIPIENT
Hindustan Abdul Ahad
Abstract
The search for a new excipient needs a lot of time and finance. The present investigation aims to extract and characterization of Psyllium (Plantago ovata) seeds and propose it as a pharmaceutical aid. The mucilage from P. ovata seeds was extracted with water and the mucilage was precipitated using Acetone (Approach-I) and 95% ethanol (Approach-II). The mucilage was characterized for physical, chemical, and micrometric characterization. FTIR spectra were also engendered for the mucilages and compared. The mucilages showed and possess all the official parameters required as a pharmaceutical excipient. Among the extractives, mucilage precipitated with acetone was partially better than ethanol precipitated. The work summarizes that P. ovata mucilage can be used as a tablet binder and viscosity-modulating agent in pharmaceutical preparations.
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