PJB-2023-606
COMPARITIVE ANALYSIS OF ANTI-MICROBIAL POTENTIAL OF ZINGIBER OFFICINALE ROSCOE (GINGER) AND ITS’ PHYTO-MEDIATED IRON NANOPARTICLES
Zeenat Fatima
Abstract
The secondary metabolites of plants have medicinal use to prevent various infections. But recently, microbial resistance is reducing the effectiveness of conventional plant medicines and synthetic antibiotics. Nanotechnology is being considered as a potential source to combat microbial resistance and enhance plants medicinal values. Green synthesized nanoparticles using ginger as plant source could enhance these properties. The ginger Fe NPs had shown maximum anti-fungal activity against all fungal strains, Alternaria alternata, Macrophomina phaseolina and Sclerotium rolfsii (at a concentration of 400 mg/L) i.e. 26 mm ± 0.3, 25 mm ± 0.2 and 25 mm ±0.3 respectively, more than ginger rhizome extract anti-fungal potential of 24 mm ± 0.2, 23 mm ± 0.3 and 23 mm ± 0.3 respectively. The ginger Fe NPs had shown maximum bacterial inhibition against all bacterial strains of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumonia (at a concentration of 400 mg/L) i.e. 25 mm ±0.3, 27 mm ±0.4, 26 mm ±0.4 and 25 mm ±0.3 respectively, more than ginger rhizome extract of same concentration had shown the anti-bacterial activity of 23 mm ±0.2, 24 mm ±0.3, 23 mm ±0.3 and 22 mm ±0.3 respectively. This indicated the enhancement of anti- microbial potential of ginger by using their green synthesized nanoparticles.
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