PJB-2024-382
In-vitro Evaluation of Anti-bacterial and Anti-fungal Activity of Murraya koenigii Shoot Extracts
Kinza Khan
Abstract
Use of herbal medicines is a common practice for treatment in various parts of the world from many centuries. Bioactive compounds of herbal extracts are used to cure many diseases especially in developing and under-developed nations because of their cost-effectiveness. Sometimes, these medicines are more effective to combat microbial infections as compared to conventional medicines. One of these medicinal plants is Murraya koenigii and which is commonly used as food additive in South Asian countries. The anti-microbial properties of Murraya koenigii shoot extracts in five different solvents was evaluated against various bacterial strains including Bacillus cereus, Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 278533), Staphylococcus aureus (ATCC 29213), Salmonella typhi (ATCC 14028) and Klebsiella pneumonia (ATCC 29213). Maximum activity against Bacillus cereus was observed in Hexane extract. Acetone extract was found to be most efficient against Pseudomonas aeruginosa. Whereas, dichloromethane extract had highest anti-bacterial activity towards Bacillus cereus. Among alcoholic extracts, maximum activity of ethanol extract was displayed against Klebsiella pneumonia & Pseudomonas aeruginosa while methanol extract exhibit maximum activity for Bacillus cereus. Antifungal activity was highest for ethanol extract against Candida albicans (ATCC60193).
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