PJB-2024-568
A BERIEF REVIEW OF THE PHYTOCHEMICAL CONSTITUENTS AND ANTIBACTERIALPOTENTIALOF TRIBULUS TERRESTRIS
MUHAMMAD KHALID AFZAL
Abstract
Tribulus terrestris (Puncture vine) is a medicinal herb found all around the world. Its therapeutic efficacy as eastern medicines have been known since ancient times. For thousands of years, TT's fruits and roots have been utilized as traditional medicine in India, Pakistan, and China. Several bioactive phytochemicals, including as flavonoids and saponins, have been discovered from Tribulus terrestris are responsible for a variety of pharmacological actions, either alone or in combination. This plant is known to have antioxidant, antibacterial, antidiabetic, antihelmint hic, larvicidal, anti-inflammatory, cardiotonic, antispasmodic, diuretic, analgesic, immunomodulator y, hepatoprotective, and anticancer activities. Phytochemical investigations have revealed significa nt differences in the amount of active compounds present in this plant, particularly the concentration of spirostanol and furostanol saponoside, which are thought to be the primary active elements involved in the therapeutic activity of Tribulus terrestris. Several in vitro investigations have shown that Tribulus terrestris extracts in both whole and fractionated forms exhibit antibacter ia l potential against Gram-positive and Gram-negative bacterial pathogens. Tribulus terrestris aqueous extract exhibited greater antibacterial properties in comparison to methanol extract and inhibited the selective bacterial growth, proposing the existence of bioactive compounds throughout a vast range in Tribulus terrestris. The current study clearly showed that Tribulus terrestris is an abundant source of phytochemicals and has excellent pharmacological properties. Therefore, it is concluded that this plant is very therapeutic and may be utilized to make powerful pharmaceuticals that are beneficial to people.
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