PJB-2024-648
ANTIDIABETIC ACTIVITY OF MULTIGRAIN COMPOSITE FLOUR OF INDIGENOUS BARLEY, BUCKWHEAT AND FABA BEAN
Syed Munir Hussain
Abstract
Food has a direct relationship with health and commonly consumed nutrients demonstrate their impact on normal body functioning. The recent job and business-oriented society; people use energy dense and junk foods for their ease in the busy schedules. This phenomenon has caused many health issues like hypertension and diabetes mellitus. The metabolic disorder characterized by insufficient insulin production is diabetes mellitus, which affects the body's ability to utilize glucose. Research is focused on overcoming this disease world over through different food remedies. Hence, this study was designed to develop a multigrain product using buckwheat, barley and faba bean as main ingredients and mulberry as flavor agent. The proximate composition of the food formula in terms of moisture, ash, protein, fiber, fat and carbohydrate was 6.71-2.51, 2.44-2.84, 9.66-11.15, 3.87-7.64, 1.34-2.24, 66.87-72.72% respectively. Among the essential micro-nutrients, iron was 49.35-120.67mg/ kg while zinc was found in the range of 16.06-28.38 mg/kg in the final product. In vivo studies on albino rates were conducted to assess the antidiabetic activity of the formula. The rates were fed with the formula after overnight fasting. The serum glucose levels were recorded before feeding and then at seven days interval till the fourteenth day. The results revealed that the blood glucose level decreased from 500 mg/dl to 100mg/dl after 7 days and 128mg/dl after 14 days. This trend shows that the feed significantly reduced the blood glucose levels and the effective remediation of diabetes through indigenous grain formula.
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