PJB-2018-538
Antifungal potential of Macrocybe gigantea against Penicillium glabrum
MS. Qudsia Firdous
Abstract
The widespread manifestation of biological activities within the fungal kingdom is now widely accepted. The study has focused on antifungal potential of the mushroom Macrocybe gigantea, a species that is native to India (West Bengal), Pakistan, and Nepal. This genus of fungi in the family Tricholomataceae has been known for its antioxidant, antibacterial and anticancer activity. For the corroboration of the species, standard identification characteristics were utilized (macroscopic and microscopic). The methanol extract of the Basidiocarp was assessed for antifungal activity against Penicillium glabrum. Extract was applied in different concentrations (0.00, 0.01, 0.02, 0.03 and 0.04) to relate best activity according to its concentration gradient. M. gigantea indicated great potential when appertain in maximum quantity (0.822 mg, 0.566 mg, 0.54 mg, 0.511 mg and 0.323mg; respectively) against P. glabrum which is a plant pathogenic fungus. The findings of the present study stipulated promising inoffensive fungicidal and related applications of M. gigantea methanolic extracts in terms of antifungal activities.
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