PJB-2018-600
PHYTOCHEMICAL COMPOSITION AND ANTIDIABETIC ACTIVITY OF AQUEOUS DECOCTION OF SELECTED MEDICINAL PLANTS
Matina Kanwal
Abstract
Abstract: The present research work was done to evaluate the chemical composition and antidiabetic activity of Foeniculum vulgare, Nigella sativa and Corriandrum sativum and their herbal tea. These plants will be mixed in equal quantities to prepare herbal tea. Antioxidant activity was determined by DPPH assay, total phenolic and flavonoid contents were determined by spectrophotometric assay while antidiabetic activity of plants and their respective tea formulation evaluated by their inhibitory potential against alpha amylase enzyme assay via in-vitro assay. The result showed that the ranges of antioxidant activity (71.26 ± 0.07 - 14.75 ± 0.14%), total phenolic content (514.75 ± 0.01 – 79.98 ± 0.11 µg GAE/g), total flavonoid content (53.81 ± 0.04 - 48.76 ± 0.09 µg QE/g) and antidiabetic activity (IC50= 14.74 – 8.49). The current work conclude that herbal tea is more beneficial against antidiabetic disease and oxidative disorder as compared to individual plants.
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