PJB-2018-893
Identification of five new triterpenoids from ethylacetate bark extract of Holoptelea integrifolia (Roxb.) Planch by GC-MS
Amir Hassan
Abstract
n-hexane soluble ethylacetate extract (HIB-EA-HS) of bark of Holoptelea integrifolia (Roxb.) Planch was analyzed on GC-MS. The identified triterpinoids included: β-sitosterol (1), olean-13(18)-ene (2), betulin (3), α-amyrenone (4), stigmasta-3, 5-diene-7-one (5), stigmast-4-en-3-one (6), friedelan-3-ol (7), and citrost-7-en-3-ol (8). Triterpenes (1), (3) and (7) have been reported previously but the other triterpenes (2), (4), (5), (7), and (8) were identified first time from the bark extract of H. integrifolia (Roxb.) Planch. Phytosteroids are an important class of natural products, and all these metabolites are quite known and common in higher plants. Important biological functions of the phytosterols induced LDL- cholesterol reducing potential and anti-colon cancer activity.
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