PJB-2018-965
Characterization of Mallotus phillipensis for its antibacterial and antioxidant activities
Rimsha Dilshad
Abstract
Phytochemicals present in medicinal plants are a major source of imparting different characteristics to the plant. Antibacterial and antioxidant activity of these bioactive compounds was tested in ethanol and ethyl acetate extracts of four medicinal plants i.e. Ziziphus jujube (Unaab), Fagonia arabica (Dhamasa Booti), Mallotus phillipensis (Kameela) and Hemidesmus indicus (Ushba). Phytochemical analysis of these plants revealed the presence of alkaloids, carbohydrates, cardiac glycosides, flavonoids, phenols, phlobatanins, reducing sugars, saponins, steroids, tannins and terpenoids in them. Agar well diffusion assay revealed maximum inhibition zone of extracts against Bacillus strain (4-11mm) while for Pseudomonas strain no considerable inhibition (1-3mm) was observed by either of the extracts. Minimum inhibitory concentration of Kameela ethyl acetate extract was 62.5mg/L. Kameela extract was found to exhibit maximum bacterial efflux pump inhibition potential (155%). Twelve components of extracts were separated by TLC. Component showing antibacterial potential was subjected to GCMS analysis which indicated phthalic acid to be the component responsible for this activity. Significant antioxidant activity was also observed from Mallotus phillipensis extract. Phthalic acid, responsible for antibacterial activity of plant extract, can be used in medicine industry to treat certain bacterial infections.
To Cite this article:
Download
