PJB-2019-570
Antibacterial and Antioxidant Activities of Oliveria decumbens Collected from the East of Iran
mina mahmoudi
Abstract
The aim of this study was to evaluate the antibacterial and antioxidant activities of Oliveria decumbens collected from the east of Iran. Firstly, the ethanolic extract of O. decumbence was prepared. Secondly, the extract evaluated for toxicity by MTT assay; then subjected for antibacterial activity via MIC and antioxidant activity via ABSTE, DPPH and FRAPS assays. Our findings demonstrated that O. decumbens extract has a high rate of phenolic content, 116 mg catechol/µl extract. This extract showed the highest antioxidant activity Inhibitory percentage of free radical DPPH in O. decumbens extract was 75.7%. Our results showed that antioxidant activity via ABTS and FRAP tests were 6.4mMol Fe2+/μl extract and 2.6 mmol Terolox/μl, respectively. MIC and MBC value of extract against indexed bacteria was equal (30μg/ml). We found considerable effects of O. decumbens extract such as antioxidant activity and antibacterial activity against P. aeruginosa, E. coli and K. pneumoniae with low cell toxicity. Finally, despite very good antibacterial and antioxidant activity of O. decumbens as a medicinal plant, but for using O. decumbens as a medical plant in clinics, we need more studies about side effects and other unwanted activities.
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