PJB-2020-118
ANTIMICROBIAL EFFECTS OF CINNAMOMUM CASSIA AND CINNAMOMUM TAMALA EXTRACTS IN DIFFERENT SOLVENTS AGAINST SKIN PATHOGENS
Dr. Farhana Maqbool
Abstract
This study was conducted to evaluate the antimicrobial effect of the bark of Cinnamomum cassia and leaves of Cinnamomum tamala, against four human skin pathogens including Staphylococcus aureus, Escherichia. coli, Aspergillus flavus and Penicillium marneffei. Solvent extracts including hexane, ethyl acetate (EtOAc), ethanol and distilled water were used by agar well diffusion method and inhibition zone were noted. Five different concentrations 170, 136, 102, 51 and 17mg mL-1 of all the extracts were used. Gas chromatography-mass spectrometry (GC-MS) was used to identify the active components of both plant extracts. The aqueous extract was found completely inactive against all the tested organisms, while the highest concentration 170 mg mL-1 of C. cassia ethyl acetate extract was more effective against Aspergillus flavus and Penicillium marneffei as it produced inhibition zones of 24mm. C. tamala ethyl acetate extracts and hexane extracts also showed good activity but less effective as compared to C. cassia ethyl acetate extract. Cinnamaldehyde was found as major component in C. cassia which was 57%, while for C. tamala, 93% Eugenol was the active component of this plant.
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