PJB-2020-137
ANTIOXIDANT ACTIVITY OF DIFFERENT PLANTS EXTRACTS AGAINST OXIDATIVE STRESS INITIATED BY NOISE POLLUTION IN ALBINO MICE
Amen hanif
Abstract
Prolonged noise exposure of chronic and acute nature produce “free radicals” that automatically improve oxidative pressure in body. Any source and kind of noise exposure that exceeds 90 dB is work as a stressor. Reactive Oxygen Species can disrupt normal cellular functions. Noise exposure also induces lipid peroxidation and yields Malondialdehyde (MDA) which is an indicator of lipid damaging processes due to free radicals. Body needs external origin antioxidants to uphold an acceptable limit of antioxidants so that an equilibrium establish for Reactive Oxygen Species. In present study Clove, kalonji and Karhi Patta’s (leaves plus seeds) were used to lessen the eminent amount of pressure in Albino Mice due to oxidation. All three plants were also evaluated for their phytochemical qualitative & quantitative determination and Scavenging activity to hunt free radicals in methanol and aqueous extracts. Our study showed that administration of these extracts after noise exposure showed antioxidant prospective for decreasing sound influence by reducing free radicals outcome.
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