PJB-2022-103
Phytotoxicity, cytotoxicity, and chemical composition of Phlomidoschema parviflorum
Razaullah, Saleha Suleman Khan, Muhammad Shah Nawaz, Viqar Uddin Ahmad and Yan Wang
Abstract
Aerial parts of Phlomidoschema parviflorum (Benth.) Vved. were investigated, which afforded eight known compounds. Compounds 1–5 were reported for the first time from P. parviflorum. Different spectroscopic techniques were employed to characterize the compounds' structures, and the structures were compared with literature data. In addition to isolation work, gas chromatography-mass spectrometry (GC-MS) was used to examine the n-hexane fraction. As a result, thirty-six known compounds were identified; notably, they were identified for the first time in this plant. Furthermore, phytotoxicity and cytotoxicity were performed on extract and fractions of P. parviflorum. DCM fraction showed significant phytotoxicity (100% growth regulation) and moderate cytotoxicity (LD50 = 160.09 µg/mL) at 100 and 1000 µg/mL doses
To Cite this article:
Razaullah, S.S. Khan, M.S. Nawaz, V.U. Ahmad and Y. Wang. 2024. Phytotoxicity, cytotoxicity, and chemical composition of Phlomidoschema parviflorum. Pak. J. Bot., 56(3): DOI: http://dx.doi.org/10.30848/PJB2024-3(27)
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