PJB-2024-1542
Phytochemical profiling and multifaceted biological activities of Persicaria hydropiper L.: a promising medicinal plant
Azhar Abbas, Muhammad Sajid, Sheher Yar, Asif Khan, Atta Ur Rahman, Muhammad Hamayun, Sajid Ali, Yong-Sun Moon and Abdulwahed Fahad Alrefaei
Abstract
Persicaria hydropiper L. is a well-known medicinal plant that has several therapeutic benefits i.e., anti-inflammatory, antioxidant and antimicrobial agent. In the present study, phytochemical profile of P. hydropiper was investigated, along with its biological activities like, antibacterial, antifungal, antioxidant, antidiabetic and nematocidal potential via; In vitro. Results revealed the presence of various metabolites, like alkaloids, which were present in all partitions. Similarly, other partitions were also rich in flavonoids, terpenoids, glycosides, steroids, carotenoids, tannins, volatile oils and phenolic compounds The mineral contents (mg/100g) were investigated in the following order; K> Na > Ca> Ni >Mg > Fe > Cu > Zn >Pb> Cr>Mn> Cd>Co. Different bacterial and fungal strains growth was investigated, among all, chloroform crude extract showed significant antimicrobial activity (p<0.05) against Escherichia coli, Staphylococcus aureus, and Streptococcus pneumonia, i.e., 23 ± 0.31mm, 8 ± 0.75mm, and 9 ± 0.76mm inhibitions, compared to the control. It was noted that ethyl acetate partition was more potent against E. coli (24±0.72mm) inhibition and A. flavus and A. fumigatus 24±2.43mm and 8±2.50mm inhibition, respectively. Additionally, fluorescence microscopy and antioxidant activities revealed prominent findings. Moreover, GC-MS analysis revealed the presence of 61 distinct compounds, with the most prevalent compounds being; Benzene Cyclo Hexyle, Sulfurus Acid, 2 Ethyl Hexyledecyle Ester, 2,4-Di-Tert-Butyl Phenol, Cyclobutanone, 2, 3, 3, 4-Tetra Methyl and Pentaoic Acid and 2-Ethyl Hexyl Ester. Hence, the presence of important phytochemicals, minerals, and resistance to different pathogens demonstrates the importance of P. hydropiper in the pharmaceutical industry
To Cite this article:
Abbas, A., M. Sajid, S. Yar, A. Khan, A.U. Rahman, M. Hamayun, S. Ali, Y.S. Moon and A.F. Alrefaei. 2024. Phytochemical profiling and multifaceted biological activities of Persicaria hydropiper L.: a promising medicinal plant. Pak. J. Bot., 56(4): DOI: http://dx.doi.org/10.30848/PJB2024-4(31)
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