PJB-2016-210
PLANT-MEDIATED GREEN SYNTHESIS OF SILVER NANOPARTICLES FOR BIOMEDICAL APPLICATIONS: CHALLENGES AND OPPORTUNITIES
SUMAIRA ANJUM, BILAL HAIDER ABBASI* AND ZABTA KHAN SHINWARI
Abstract
Metallic nanoparticles are an emerging class of functional materials, revolutionizing all domains of human life making nanotechnology, a promising arena for biomedical applications. Among the metallic nanoparticles, Silver nanoparticles (AgNPs) represent one of the most comprehensively studied nanomaterials. The current development and execution of new technologies have led to new era, the nano-revolution which discloses the role of plants in green synthesis of nanoparticles and have drawn fairly an undeniable attention with a vision of synthesizing stable and eco-friendly nanoparticles. Employing plant extracts toward synthesis of AgNPs are emerging as advantageous over other conventional methods due to low-cost, energy-efficient, non-hazardous, and environmentally tolerable along with the manifestation of broad variability of biomolecules in plants, which can act as reducing and capping agents. Biologically synthesized AgNPs have upsurge applications in various sectors such as electronics, clothing, food industry, paints, sunscreens, cosmetics, biosensing, medicines, drug delivery and medical devices. Broad-spectrum bioactivities of AgNPs indicate their potential to solve many microbial resistance problems. The antibacterial, antifungal, antiviral, antiprotozoal, anti-inflammatory and anticancer activities of AgNPs have recently engrossed the attention of scientists. The aim of the present review is to discuss the plant mediated green synthesis of AgNPs and mechanistic aspects involved in reduction and stabilization of AgNPs. Methods of AgNPs characterization are reviewed and broad-spectrum multifunctional activities of AgNPs and their potential biomedical applications are discussed. This review also focuses on the assessment of impending human and ecosystem deathtraps associated with increased utilization of AgNPs and the safety issues concerning their biomedical applications.
To Cite this article:
Download
