Paper Details

PJB-1969-2

CAUSES OF THE FORMATION OF AN ABNORMALLY HIGH PROPORTION OF PROTOTROPHS IN SOME INTERALLELIC CROSSES OF NEUROSPORA CRASS

MAJEED AIIMAD, M. ISLAM AND R. KIIANAM
Abstract


Causes of the formation of a high frequency of prototrophs in inter allelic crosses of three tryptophan-1 mutants and one tryptophan-3 mutant have been investigated. The high frequency of prototrophs in the inter allelic crosses of the three tryptophan-l mutants follows from the formation of a large number of pseudo-wild spores. But the formation of an abnormally high proportion of prototrophs in the interallelic crosses of the single tryptophan-3 mutant, A30S, cannot be explained on the basis of pseudo-wild formation, action of recombination, accelerating genes, unequal crossing over, reversion of suppressors. It seems that the. tryptophan synthetase formed by the damaged tryptophan-3 locus in this mutant can acquire a functioned configuration as a result of the action of some other genes which act as modifiers.

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